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Chemotherapy and hair loss: What to expect during treatment

Can hair loss be prevented?

No treatment exists that can guarantee your hair won't fall out during or after chemotherapy. Several treatments have been investigated as possible ways to prevent hair loss, but none has been absolutely effective, including:

  • Scalp cooling caps (scalp hypothermia). During your chemotherapy infusions, a closely fitted cap that's cooled by chilled liquid can be placed on your head to slow blood flow to your scalp. This way, chemotherapy drugs are less likely to have an effect on your hair.

    Studies of scalp cooling caps and other forms of scalp hypothermia have found they work somewhat in the majority of people who have tried them. However, the procedure also results in a very small risk of cancer recurring in your scalp, as this area doesn't receive the same dose of chemotherapy as the rest of your body. People undergoing scalp hypothermia report feeling uncomfortably cold and having headaches.

  • Minoxidil (Rogaine). Applying minoxidil — a drug approved for hair loss — to your scalp before and during chemotherapy isn't likely to prevent your hair loss, although some research shows it may speed up your hair regrowth. More research is needed to understand whether minoxidil is effective in regrowing hair after cancer treatment.